I make an insecticidal tea for spider mites and other bugs. I soak tobacco and buffalo sage in water, then add a small amount of dish soap (to break down surface tension on the pests). All surfaces of the plant have to be sprayed top and bottom, plus the soil, but it’s effective. Keep in fridge for future use.
My theory is that the more variety of bug toxic compounds, the greater the effect, due to synergy.
Just examine the local plant communities for aromatics that bugs never bother, there’s probably toxins there.