Go check em. Right now… I mean it. Stop reading right now, go outside, and put a wrench on your lug nuts. All 4 wheels, just as tight as you can get them. I’ll wait.
Back now? OK… well because I have been less than diligent doing the above, I found myself on the side of the road yesterday. The left rear tire came completely off (I actually saw the lug nuts fly off in my mirror). Fortunately I was only going about 45 on a country road, with wide shoulders. Also very fortunate, the brake drum landed inside the rim, and the wheel stayed under it as I got off the road. Yes it could have been much worse!
I think the culprit is my pretty aluminum wheels… aluminum is soft and over time can loosen up. This is why they banned aluminum house wiring in the 1970s - too many loosened up wiring / arcing / wall fires.
But really, they’re not so bad if you keep checking. And that’s what I didn’t do. Even steel wheels will come loose if you don’t pay attention. This now goes on my regular maintenance list.
Other things to check - make sure the jack in your truck will in fact lift the vehicle (I was missing a handle), make sure you have jumper cables, and be sure your lug wrench actually fits the lugs (mine was close but not perfect).
All that said, I had a great trip apart from that, the gasifier did fine, and I got the transmission I was after. I also checked my lug nuts about 5 times on the way up there… a bit paranoid now I guess.