Good morning all.
I was thinking of a year ago today.
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It always is a lot of fun. I miss it 
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Erika and Lisa fed us well. I looked fat 
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weâve got a dozen swallows and sparrows nesting on our farm. not sure about good people but we definitely have mosquitoes 
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the Razinger jaw stone crusher from 1953, which I adapted for driving with a tractor, grinds about 3 m3 / hour depending on the granulation, so it looks like âŚ
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How big of rocks can you put through that thing.
the opening is 25 * 40 cm, ⌠but I still have to finish the dosing table and the conveyor belt
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What kind of trees are those?
Great if you want to break up the slab, otherwise itâs time for a chainsaw massacre⌠
I donât know but any trees will do that with enough neglect. Around here it is common for maples because the seeds are so small.
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After a cold spring itâs suddenly terribly hot, 31°C (88°F), in Sweden. Fruit tree flowers are exploding and chunks are drying in no time. Tar draining is about all I managed to do in this heat.
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Ha! Ha! Same here for us J.O.
Riding the Polar Vortex is just like small boating in sea estuaries. Tides. Winds. Endure. Persevere the bobbing to still be out fishing.
Know when to just quit and hunker down.
Our 31C (88F) was two weeks ago. ( not a record)
Now two days of almost cold 50âsF raining.
Cleared up sky last night had a radiation dropped almost-frost of 36F this morning.
A-l-m-o-s-t a new vegetable garden 10 days set-back.
Expecting #10 perfect weather for the next 5 days now. Wonderful.
Learn to ride and love those waves. Mediterranean/SoCal, same-same for the majority of the time would be so boring. Leads to fantasying unrealistic expectations of how the real world functions.
S.U.
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Mostly silver maple . All trees in foreground growing along concrete footing . Said to have been 5 car garage . No description for what all the other buildings might have been . One part I will call "Pollinator overlook " because it over looks acre of bee balm . Pines in background are also mine
past two rows of fence . I am cutting trees over hanging fence . I am just cutting to have access .
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Nice place you have, Henry!.. 
Iâm just proud to say we here in Indiana are having our one-month-postponed primary election today. I voted on Saturday, actually, because it was convenient. We had more available opportunities to vote because of that c-19 thing. (wasnât that a WWII cargo plane? 
) So, donât forget to exercise your God-given rights and donât let the lying news media get you down. I can say that because I see the lies and the anti-constitution agenda daily. I canât quite get away from that. As Bugs Bunny used to say: Ehhh. Itâs a livinâ⌠
God Bless All of You!
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I started this project. i was reimbursed for my efforts . I think it was catch and kill . A lot of reading . Originally it was respiratory but I want it to be treatment of pink eye , so I messed the thing up .
Defense Advanced Research Projects AgencyProgram Information
Pathogen Predators (Archived)
Dr. Kerri Dugan
The Pathogen Predators program focuses on force readiness and homeland protection through development of novel countermeasures against biological threats involving bacterial agents. Currently, the most common defense against such a threat is traditional antibiotics, but while such antibiotics have been remarkably effective in the past, their widespread use has heightened the risk of our troops contracting antibiotic-resistant bacterial infections that are difficult or impossible to treat. A new type of countermeasure is needed to overcome the threat posed by antibiotic-resistant bacteria.
Pathogen Predators aims to develop a new class of dynamic therapeutics that use live, motile, predatory bacteria that prey upon other Gram-negative bacteria that are pathogenic to humans. Previous in vitro studies have shown that predators such as Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus prey upon more than 100 different human pathogens, including several that are multi-drug resistant. These results suggest that it is possible to develop a predator-based therapeutic with efficacy against a broad spectrum of Gram-negative pathogens, including those that are resistant to antibiotics.
The Pathogen Predators program seeks to establish the technical feasibility of such an approach for use in humans. The program supports fundamental research aimed at developing a molecular-level understanding of predator-prey interactions as well as studies using in vivo infectious disease models. Specifically, Pathogen Predators seeks to determine if predators are toxic to recipient (host) organisms; against what pathogens (prey) predators are effective; and if pathogens can develop resistance to predation over time.
If successful, Pathogen Predators will lay the groundwork for a living, predator-based therapeutic that is safe and efficacious against a large number of infectious diseases, including those that are resistant to conventional treatments. Future advances in this area may be also applied to a range of biological technologies including the autonomous control of epidemics.
Defense Advanced Research Projects AgencyProgram Information
Pandemic Prevention Platform (P3)
Dr. Amy Jenkins
The Pandemic Prevention Platform (P3) program aims to support military readiness and global stability through pursuit of novel methods to dramatically accelerate discovery, integration, pre-clinical testing, and manufacturing of medical countermeasures against infectious diseases. P3 confronts the reality that Department of Defense (DoD) personnel are not only deployed around the world for routine operations, but are often among the first responders to outbreaks of emerging or re-emerging disease with pandemic potential (e.g., Ebola). P3 aims specifically to develop a scalable, adaptable, rapid response platform capable of producing relevant numbers of doses against any known or previously unknown infectious threat within 60 days of identification of such a threat in order to keep the outbreak from escalating and decrease disruptions to the military and homeland. State-of-the-art medical countermeasures often take many months or even years to develop, produce, distribute, and administer. The envisioned P3 platform would cut response time to weeks and stay within the window of relevance for containing an outbreak.
P3 focuses on rapid discovery, characterization, production, testing, and delivery of efficacious DNA- and RNA-encoded medical countermeasures, a foundational technology pioneered by DARPA under the Autonomous Diagnostics to Enable Prevention and Therapeutics (ADEPT) program that provides the body with instructions on how to immediately begin producing protective antibodies against a given threat. The P3 program seeks to unlock the potential of these coded genetic constructsâestablishing them as the basis for a threat-agnostic platform technologyâby achieving and integrating breakthroughs in three key areas: novel approaches for the growth of viruses for use in testing and evaluation of countermeasures; rapid identification and maturation of protective antibodies to increase their potency; and novel technologies for the delivery of nucleic acid constructs into patients to encode the antibody of interest and produce a protective response.
A principal benefit of the nucleic-acid-based approach to limiting the spread of infection is that genetic constructs introduced into the body would process quickly and not integrate into an individualâs genome. Similarly, the antibodies produced in response to treatment would only be present in the body for weeks to months. This is consistent with DARPAâs intent to safely deliver transient immunity, halting the spread of disease by creating a firewall, and buying time for longer-term medical responses to be developed and deployed.
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I have alone funded research by Oklahoma State university veterinary school Dr. Melanie Boileau use of Bdellovibrio bacteriovorus 109j to treat Infectious bovine Keratoconjutivitis killing Moraxella bovis .
the use of a predatory bacteria to treat a bacterial infection. An alternative to antibiotic treatments.
I want my legacy to be that I funded this and that this becomes a new field of medicine.
I gave $200,000. so that testing in live animals cattle could be done.
I was assured that this was what was going to be done.
I would like to know If testing on cattle is or ever was intended.
Microbiologist Robert Shanks, an associate professor at the University of Pittsburgh in Pennsylvania, first heard of predatory bacteria as a postdoctoral researcher working in the same lab as Kadouri. Now, Shanks studies Bdellovibrioâs potential to treat eye infections. These infections, caused by P. aeruginosa, Serratia marcescens, and other drug-resistant gram-negative pathogens, can occur on the eyeâs surface in contact lens wearers or deep within the eye when microbes cross the blood-brain barrier.
Shanks and his team have found Bdellovibrio can consume several pathogens isolated from human infections and appear to be nontoxicâand even noninflammatoryâin rabbit studies. Preliminary data from their team show that âthe predatory bacteria [speed] up clearance of the pathogen from the ocular surface,â Shanks says. âThey donât work as well as an antibiotic, but they are much better than no antibiotic.â Although the predatory bacteria donât completely eliminate pathogens in their studies, they may drive pathogen levels low enough to give the immune system a fighting chance, he says.
The testing was done it failed .
This is not science . Science is when you repeat .
Yes I need to do more reading .
https://mbio.asm.org/content/8/5/e00959-17#ref-list-1
Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1-Year Period
The most promising results obtained with the computational model are related to a high initial proportion of the predator, simulating an artificial addition as could happen if predators were used as a biological weapon. All of the bacterial species were eliminated with this condition; first, prey are destroyed by predators and then predators become extinct because of the absence of nutritional sources, suggesting that Bdellovibrio might eventually be used as a âbiological antibiosis strategyâ to control pathogenic bacterial populations (59), at least in the early stages of the colonization process, when the prey density is still low. The safety of these microorganisms has been demonstrated in animals
Infection Prevention and Control Assessment Tool for Nursing Homes Preparing for COVID-19
Pathogen detected (select all codes that apply): In the space provided, record the code that corresponds to the bacterial and/or viral organisms that were identified through laboratory testing. If the test performed was negative, indicate âzeroâ. If a pathogen not listed was identified through laboratory testing, please use the space provided by âOtherâ to specify the organism.
0 â Negative results; Bacterial: 1 â Streptococcus pneumoniae, 2 â Legionella, 3 â Mycoplasma
Viral: 4 â Influenza, 5 â Respiratory syncytial virus (RSV), 6 â Human metapneumovirus (HMPV), 7 â Other: Specify
(1) Bacterial co-infections are the hidden threat lurking behind COVID-19
Already, some studies have found that 1 in 7 patients hospitalized with COVID-19 has acquired a dangerous secondary bacterial infection (Zhou et al., 2020). These co-infected patients have a higher risk of mortality according to reports that 50% of COVID-19 patient deaths were due to secondary infections (Morris, Cleary, Clarke 2020, Zhou et al., 2020). Approximately 20-30% of hospitalized patients co-infected with COVID-19 and pneumonia have required intensive care for respiratory support (Huang et al., 2020, Wang et al., 2020). Treatment of severely ill patients with mechanical ventilation is known to increase the risk of bacterial infections, and where antimicrobial resistance is rampant, even higher risks for complications and mortality can be expected.
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I now have a working chainsaw . I bought this at Sears 10 years ago . It has been sitting for 5 years because I could not find a chain for it . I think I was sold wrong replacement chain when I bought it .
I kept buying wrong chain and gave up . I found the right chain on Amazon . Husqvarna said they are out of stock .
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https://www.baileysonline.com/
That is where I go for all my chainsaw needs. I highly recommend the 18 inch organ power match bars. I think they have a different name for them now but the top end light organ bar has proven to be well worth the cost I can run the lighter longer bar and still have a nice weight balance on that size saw. My uncle runs just about the same saw you have.
Oh I just checked the model you have a bigger saw but the power match bars are still well worth it in my opinion. I run one on my large stihl MS460 and when the OEM bar on my MS261 dies it will be replaced with one.
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I have a stihl MS251C and used over a half dozen chains . Last year I paid $75 to have it fixed , still using it to cut through concrete , cutting down trees growing in concrete . The 20 inch bar was half the size I needed for the tree that enveloped my house .
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